
Parathyroid Hormone (1-34), bovine
CAS No. 12583-68-5
Parathyroid Hormone (1-34), bovine( —— )
Catalog No. M33742 CAS No. 12583-68-5
Parathyroid Hormone (1-34), bovine, a parathyroid hormone (PTH) receptor agonist from the parathyroid hormone family, is used to study osteoporosis and hypoparathyroidism.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 135 | Get Quote |
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5MG | 187 | Get Quote |
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10MG | 282 | Get Quote |
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25MG | 453 | Get Quote |
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50MG | 660 | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameParathyroid Hormone (1-34), bovine
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NoteResearch use only, not for human use.
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Brief DescriptionParathyroid Hormone (1-34), bovine, a parathyroid hormone (PTH) receptor agonist from the parathyroid hormone family, is used to study osteoporosis and hypoparathyroidism.
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DescriptionParathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis.
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In VitroParathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) are added to the medium, it inhibits osteoblast proliferation in a dose-dependent manner. In another group, bPTH are added to the culture medium from day 1 to day 10, but not from days 11 to 20, a rebound of proliferation is observed in the PTH Day 1–10 group after bPTH withdrawal.Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) induces diverse effects on the calcium and phosphorus content of culture medium. The calcium and phosphorus content of culture medium in the PTH-C 100 ng/mL group are higher than in teh control group.Cell Proliferation Assay Cell Line: MC3T3-E1 cells Concentration:0.1-100 ng/mL Incubation Time:2-20 days Result:Resulted a decrease of osteoblast proliferationin concentration-dependent manner.
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In VivoParathyroid Hormone (1-34)(subcutaneous?injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals.?Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetTHR
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RecptorThyroid hormone receptor(THR)
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Research Area——
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Indication——
Chemical Information
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CAS Number12583-68-5
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Formula Weight4104.39
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Molecular FormulaC183H288N54O50S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 50 mg/mL (12.17 mM; Ultrasonic)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. B H Mitlak, et al. Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res. 1992 May;7(5):479-84.?
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