
Parathyroid Hormone (1-34), bovine
CAS No. 12583-68-5
Parathyroid Hormone (1-34), bovine( —— )
Catalog No. M33742 CAS No. 12583-68-5
Parathyroid Hormone (1-34), bovine, a parathyroid hormone (PTH) receptor agonist from the parathyroid hormone family, is used to study osteoporosis and hypoparathyroidism.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 135 | Get Quote |
![]() ![]() |
5MG | 187 | Get Quote |
![]() ![]() |
10MG | 282 | Get Quote |
![]() ![]() |
25MG | 453 | Get Quote |
![]() ![]() |
50MG | 660 | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameParathyroid Hormone (1-34), bovine
-
NoteResearch use only, not for human use.
-
Brief DescriptionParathyroid Hormone (1-34), bovine, a parathyroid hormone (PTH) receptor agonist from the parathyroid hormone family, is used to study osteoporosis and hypoparathyroidism.
-
DescriptionParathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis.
-
In VitroParathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) are added to the medium, it inhibits osteoblast proliferation in a dose-dependent manner. In another group, bPTH are added to the culture medium from day 1 to day 10, but not from days 11 to 20, a rebound of proliferation is observed in the PTH Day 1–10 group after bPTH withdrawal.Parathyroid Hormone (1-34), bovine (0.1-100 ng/mL; 2-20 days) induces diverse effects on the calcium and phosphorus content of culture medium. The calcium and phosphorus content of culture medium in the PTH-C 100 ng/mL group are higher than in teh control group.Cell Proliferation Assay Cell Line: MC3T3-E1 cells Concentration:0.1-100 ng/mL Incubation Time:2-20 days Result:Resulted a decrease of osteoblast proliferationin concentration-dependent manner.
-
In VivoParathyroid Hormone (1-34)(subcutaneous?injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals.?Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls.
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetTHR
-
RecptorThyroid hormone receptor(THR)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number12583-68-5
-
Formula Weight4104.39
-
Molecular FormulaC183H288N54O50S2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?H2O : 50 mg/mL (12.17 mM; Ultrasonic)
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. B H Mitlak, et al. Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res. 1992 May;7(5):479-84.?
molnova catalog



related products
-
AH-3960
AH-3960 is an thyroid hormone receptor-1 (PTHR1) agonist.
-
Parathyroid Hormone ...
Parathyroid Hormone (1-34), bovine, a parathyroid hormone (PTH) receptor agonist from the parathyroid hormone family, is used to study osteoporosis and hypoparathyroidism.
-
Methimazole
Methimazole(Tapazole, Northyx) is an antithyroid medicine.